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中文摘要：
目的：了解近几年深圳市龙岗区围产儿出生缺陷发生率及变化趋势,为降低出生缺陷发生率、提高出生人口素质提供依据。方法：对2004～2009年出生缺陷监测资料进行回顾性分析。结果：2004～2009年龙岗区围产儿出生缺陷发生率为13.05‰,流动人口出生缺陷发生率高于常住人口;男性围产儿出生缺陷发生率为14.15‰,女性发生率为11.50‰,男性出生缺陷发生率比女性发生率高;常见出生缺陷类型为先天性心脏病、多指（趾）及总唇裂;出生缺陷中的死胎、死产导致死亡构成比呈下降趋势（χ2=38.19,P〈0.000 1）,新生儿存活构成比则呈上升趋势（χ2=36.65,P〈0.000 1）。结论：积极开展三级预防,采取综合干预措施,降低出生缺陷的发生率。
英文摘要：
Objective：To understand the incidence and change trend of perinatal birth defects in Longgang district of Shenzhen city in recent years,provide a basis for reducing the incidence of birth defects and improving the quality of birth population. Methods：The monitoring data of birth defects in Longgang district from 2004 to 2009 were analyzed retrospectively. Results：From 2004 to 2009,the incidence of birth defects in Longgang district was 13.05‰,the prevalence of birth defects of floating population was higher than that of permanent resident population;the incidences of birth defects of male perinatal infants and female perinatal infants were 14.15‰ and 11.50‰,respectively,the incidence of birth defects of male perinatal infants was higher than that of female perinatal infants;the common types of birth defects included congenital heart disease,polydactyly,cleft lip or/and cleft palate.The proportion of perinatal death induced by fetal death and stillbirth showed a decreasing trend（χ2=38.19,P0.000 1）,the proportion of survival neonates showed a increasing trend（χ2=36.65,P0.000 1）. Conclusion：Carrying out tertiary prevention actively and adopting comprehensive interventional measures contribute to reducing the incidence of birth defects.
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