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中文摘要：
间质干细胞（mesenchymal stem cells,MSCs）是来源于中胚层的一类具有高度自我更新能力和多向分化潜能的非造血干细胞,具有很好的组织迁移能力和肿瘤靶向性。MSCs用于抗肿瘤治疗已经开展了广泛的研究,MSCs可以作为细胞载体发挥抗肿瘤作用,同时通过促肿瘤血管生成、免疫抑制、分化为肿瘤相关成纤维细胞等方式促进肿瘤的恶性行为。该文对近年来该领域的研究进展进行简要综述。
英文摘要：
Mesenchymal stem cells（MSCs）,with a high degree of self-renewal and differentiation potential and well organized migration and tumor targeting,are from the mesoderm and are a class of non-hematopoietic stem cells.Extensive research has been carried out in the anti-tumor therapy of MSCs.MSCs can be used as a cell vehicle to resist tumots,meanwhile MSCs can promote malignant behavior of tumor by promoting tumor angiogenesis,immunesuppression and differentiating to tumor-associated fibroblasts.This article is a brief overview of the research progress in recent years in the field.
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