目的:比较胸部肿瘤调强放射治疗(IMRT)与常规放射治疗(CRT)剂量-体积直方图(DVH)参数及动态心电图( DCG)的改变情况。方法选择72例胸部肿瘤患者,根据治疗方案分为IMRT组和CRT组,每组36例,分别于治疗前、中、后进行24 h DCG监测,分析两组DVH参数及DCG改变情况。结果 IMRT组心脏V30、V40、V50均明显低于CRT组,差异有统计学意义( P<0.01),IMRT组及CRT组治疗前、中、后DCG异常发生率比较,差异有统计学意义( P<0.01),治疗中、后IMRT组DCG异常发生率均低于CRT组,差异有统计学意义(P<0.05)。结论两种治疗方法均可引起DCG改变,但在相同剂量照射时,IMRT组心脏受照体积减少,对DCG影响更小。
Objective To compare the dose volume histogram ( DVH) parameters and dynamic electrocardio-gram( DCG) changes between intensity modulated radiotherapy ( IMRT) and conventional radiotherapy ( CRT) for the thoracic tumor.Methods The patients with thoracic tumors were divided into IMRT group and CRT group ,with 36 cases in every group , two groups were tested with 24-hour DCG before , during and after treatment to compare DVH parameters and DCG changed .Results Heart V30-V50 in IMRT group were significantly lower than that in the CRT group, with statistical significance ( P〈0.01 ) , the abnormity incidence rates of DCG was statistically significant be-tween IMRT group and CRT group(before, during and after treatment)(P〈0.01), the abnormity incidence rates of DCG were lower in IMRT group than that of CRT group during and after treatment , with statistical significance ( P〈0.05 ) .Conclusion Both treatments can cause DCG change , but at the same dose IMRT group has smaller heart ir-radiation volume and lighter change of DCG .