目的了解健康体检人群中女性宫颈非典型鳞状细胞(ASCUS)的检出情况并对其相关因素进行分析。方法选择2011年1月—2013年12月在贵阳医学院附属医院体检中心接受体检的健康妇女29 080例,均进行常规妇科检查、阴道分泌物检查、宫颈脱落细胞检查。分析不同年龄段妇女宫颈ASCUS检出率,不同生殖道感染类型(细菌性阴道病、滴虫性阴道炎、真菌性阴道炎、子宫颈糜烂样改变、宫颈肥大并纳氏囊肿)与宫颈ASCUS检出率的关系及宫颈ASCUS的影响因素。结果宫颈ASCUS 359例,检出率1.23%。不同年龄段妇女宫颈ASCUS检出率比较,差异有统计学意义(P〈0.05)。20~29岁与50~59岁年龄段比较,差异有统计学意义(χ2=7.772,P=0.005);30~39岁与40~49岁年龄段比较,差异有统计学意义(χ2=8.596,P=0.003);30~39岁与50~59岁年龄段比较,差异有统计学意义(χ2=24.014,P〈0.001);40~49岁与50~59岁年龄段比较,差异有统计学意义(χ2=5.200,P=0.023);50~59岁与60~84岁年龄段比较,差异有统计学意义(χ2=4.053,P=0.044)。滴虫性阴道炎者宫颈ASCUS检出率高于无滴虫性阴道炎者,子宫颈糜烂样改变者宫颈ASCUS检出率高于无子宫颈糜烂样改变者,宫颈肥大并纳氏囊肿者宫颈ASCUS检出率高于无宫颈肥大并纳氏囊肿者(P〈0.05)。细菌性阴道病、真菌性阴道炎者宫颈ASCUS检出率与无细菌性阴道病、真菌性阴道炎者比较,差异无统计学意义(P〉0.05)。Logistic回归分析显示,滴虫性阴道炎、子宫颈糜烂样改变、宫颈肥大并纳氏囊肿与宫颈ASCUS的发生有回归关系(P〈0.05)。结论不同年龄段ASCUS检出率不同,滴虫性阴道炎、宫颈糜烂样改变、宫颈肥大并纳氏囊肿是引起宫颈ASCUS的高危因素,因此定期宫颈细胞学检查、及时治疗滴虫性阴道炎及宫颈病变是预防宫颈癌的重要途径。
Objective To understand the detection rate of ASCUS and its relative factors among healthy checkup population. Methods 29 080 healthy women who received health examination in department of physical checkup center in the Affiliated Hospital of Guiyang Medical College from January 2011 to December 2013,were selected as study subjects. All cases received routine gynecological examination, examination of vaginal secretions, cervical smear cytological examination. The ASCUS detection rate of different age groups,the relationship between different types of reproductive tract infection( bacteria vaginosis,trichomonas vaginitis,colpomycosis,cervical erosion changes,cervical hypertrophy complicated with nessler's cyst)and the ASCUS detection rate, and influence factors for ASCUS were analyzed. Results Among 29 080 women,359 had ASCUS,the detection rate of ASCUS was 1. 23%. There was no significant difference in the detection rate of ASCUS among different age groups( P〈0. 05). There was no significant difference in the detection rate of ASCUS between 20- 29 year groupand 50- 59 year group( χ2= 7. 772,P = 0. 005); there was significant difference in the detection rate of ASCUS between 30-39 year group and 40- 49 year group( χ2= 8. 596,P = 0. 003); there was significant difference in the detection rate of ASCUS between 30- 39 year group and 50- 59 year group( χ2= 24. 014,P 0. 001); there was significant difference in the detection rate of ASCUS between 40- 49 year group and 50- 59 year group( χ2= 5. 200,P = 0. 023); there was significant difference in the detection rate of ASCUS between 50- 59 year group and 60- 84 year group( χ2= 4. 053,P = 0. 044). The detection rate of ASCUS among women with trichomonas vaginitis was significantly higher than that among women without trichomonas vaginitis,the detection rate of ASCUS among women with cervical erosion changes was significantly higher than that among women without cervical erosion changes,the detection rate of ASCUS among women with cervi