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肺通气功能程度与慢性阻塞性肺疾病患者夜间低氧发生的相关性分析

ISSN号：1673-6273
期刊名称：《现代生物医学进展》
时间：0
分类：R563.3[医药卫生—呼吸系统;医药卫生—临床医学;医药卫生—内科学]
作者机构：[1]陕西省西安市第二医院呼吸内科,陕西西安710036
相关基金：西安市卫生局科研项目（2012004）

作者：宋爱玲[1], 卜丽娜[1], 贾卫红[1], 韩燕燕[1], 杨栋才[1], 温鸿请[1]

关键词：肺通气功能, 夜间低氧, 慢性阻塞性肺疾病, Pulmonary ventilation function, Nocturnal hypoxia, Chronic obstructive pulmonary disease

中文摘要：

目的：研究肺通气功能程度与慢性阻塞性肺疾病患者夜间低氧发生的相关性.方法：选取2012年1月至2013年6月我院治疗的60例稳定期慢性阻塞性肺疾病患者,按肺通气功能分为轻度、中度、重度、极重度4组,每组15例,监测记录研究对象肺通气功能指标及夜间血氧指标,比较各组监测指标的差异,并分析其相关性.结果：不同病情程度COPD患者FEV1/FVC、FEV1、FVC、PEF、RV、RV/TLC、MsaO2、ODI、WsaO2、LsaO2、SIT90％有差异（P＜0.05）;极重度和重度比较FEV1/FVC、FEV1、RV、MsaO2、ODI、WsaO2、LsaO2、SIT90％有差异（P＜0.05）;极重度和中度比较FEV1/FVC、FEV1、FVC、PEF、RV、RV/TLC、MsaO2、ODI、WsaO2、LsaO2、SIT90％有差异（P＜0.05）;极重度和轻度比较FEV 1/FVC、FEV1、FVC、PEF、RV、RV/TLC、MsaO2、ODI、WsaO2、LsaO2、SIT90％有差异（P＜0.05）;重度和中度比较FEV1/FVC、FEV1、FVC、PEF、RV/TLC、MsaO2有差异（P＜0.05）;重度和轻度比较FEV1/FVC、FEV1、FVC、PEF、RV/TLC、MsaO2、ODI、LsaO2有差异（P＜0.05）;中度和轻度比较FEV1/FVC、FEV1、FVC、PEF、ODI有差异（P＜0.05）.COPD患者的肺通气功能FEV1与MsaO2呈正相关（r=0.683,P＜0.05）.结论：肺通气功能程度与慢性阻塞性肺疾病患者夜间低氧发生具有相关性.

英文摘要：

Objective： To study thecorrelation between the degree of pulmonary ventilation function and nocturnal hypoxia occurs in patients with chronic obstructive pulmonary disease. Methods： Selected 60 patients with stable chronic obstructive pulmonary disease- from January 2012 to June 2013 in our hospital, divided into mild, moderate, severe, very severe four groups by pulmonary function, 15 cases in each group, monitoring records studied pulmonary function indicators and nocturnal oxygen index, comparing the differences of indicators in each group, and analyze their relevance. Results： Among four groups COPD FEV1/FVC, FEV1, FVC, PEF, RV, RV / TLC, MsaO2, ODI, WsaO2, LsaO2, SIT90% had differences （P〈0.05）;compared very severe and severe group FEV1/FVC, FEV1, RV, MsaO2, ODI, WsaO2, LsaO2, SIT90% had differences （P〈0.05）; compared very severe and moderate group FEV1/FVC, FEV1, FVC, PEF, RV, RV / TLC, MsaO2, ODI, WsaO2, LsaO2, SIT90% had differences （P〈0.05）;compared very severe and mild group FEV1/FVC, FEV1, FVC, PEF, RV, RV / TLC, MsaO2, ODI, WsaO2, LsaO2, SIT90% had differences （P〈0.05） ; compared severe and moderate group FEV1/ FVC, FEV1, FVC, PEF, RV / TLC, MsaO2 had differences （P〈0.05）; compared severe and mild group FEV1/FVC, FEV1, FVC, PEF, RV / TLC, MsaO：, ODI, LsaO： had differences （P〈0.05）; compared moderate and mild group FEV1/FVC, FEV1, FVC, PEF, ODI had differe- nces （P〈0.05）. Pulmonary function in patients with COPD MsaO2 was positively correlated with FEV1 （r = 0.783, P〈0.05）. Conclusion： pulmonary ventilation function correlated with the degree of chronic obstructive pulmonary disease in patients with nocturnal hypoxia.

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