中文摘要：

目的分析参芎葡萄糖注射液不良反应／事件（ADR／ADE）发生的特点，为临床合理用药提供依据。方法提取2012-2014年重庆市药品不良反应监测中心接收的529例参芎葡萄糖注射液ADR/ADE报告，利用Excel表及人工筛查的方法进行回顾性分析。结果在529例参芎葡萄糖注射液ADR／ADE报告中，“新的”ADR/ADE有262例（49．5％），其中“新的严重的”有18例（3．4％）；男性236例（44．6％），女性292例（55.2％），1例性别不详；60岁以上老年人比例较高（49．1％）；86．2％的患者在用药30min内发生ADR／ADE：不良反应主要表现为瘙痒、皮疹、过敏样反应、心悸、恶心等。结论参芎葡萄糖注射液新的ADR／ADE较多,应密切关注用药30min内的临床表现，加强ADR／ADE的监测，提高用药安全性。

英文摘要：

AIM To study the characteristics of adverse drug reactions/events （ADR/ADE） induced by Shenxiong glucose injection and provide reference for clinical rational medication. METHODS Totally 529 ADR/ADE induced by Shenxiong glucose injection and reported to Chongqing Center for Adverse Drug Reaction Monitoring from 2012 to 2014 were retrospectively analyzed by Excel and artificial screening. RESULTS Among 529 ADR/ADE, there were 262 new ADR/ADE （49.5%） and especially 18 new and serious ADR/ADE （3.40%） ; 236 male patients （44.6%） and 292 female patients （55.2%） were involved with 1 case of sex unknow; the proportion of the old （≥ 60 years） were largest （49.1%） ; 86.2% of the ADR/ADE happened within 30 min of medication; the main clinical manifestations of ADR/ADE were itching, rash, anaphylactoid reaction, palpitation, and nausea. CONCLUSION The new more, and it is necessary to pay attention to clinical features monitoring of ADR/ADE to enhance the medication safety. ADR/ADE of Shenxiong glucose injection are within 30 min of injection and strengthen