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中文摘要：
目的：探讨血清胱抑素C（Cys C）、血脂及血糖联合诊断在动脉粥样硬化（AS）患者病情评估中的临床效果.方法：将174例AS患者根据Gensini积分分为A组[轻度病变（≤3分）] 53例、B组[中度病变（3.01-32.67分）] 82例、C组[重度病变（32.68~180.00分）] 39例,分别统计三组患者的性别、年龄、BMI、SBP、DBP、吸烟、饮酒等一般资料,同时检测三组患者的各项血脂和血糖指标,比较三组患者各指标水平,并采用多因素Logistic回归分析其与AS病情程度相关性.结果：C组患者血清Cys C、TC、TG、FPG及2h PBG水平明显高于A组和B组（P〈0.05）,同时B组明显高于A组（P〈0.05）.多因素Logistic回归分析显示,血清Cys C、TC、TG、FPG及2h PBG是AS病情加重的独立危险因素（OR分别为4.183、3.785、2.967、3.108、3.474）.结论：AS患者的血清Cysc、血脂及血糖水平与病情严重程度呈明显正相关,联合检测能有效评估患者病情,为临床诊断及治疗提高指导,具有重要的价值.
英文摘要：
Objective：To study the serum CysC, blood lipid and blood glucose in the diagnosis of atherosclerosis （AS） patients with clinical effect assessment of the illness.Methods： 174 AS patients according to the Gensini score of all patients were divided into mild lesions （less than 3）, moderate （lesions 3.01~32.67）, severe lesions （32.68~180.00）, group A （53 cases）, B group （82 cases）, C group （39 cases）, statistics of three groups of patients with gender, age, BMI, SBP,DBP, smoking, drinking and other general information, the simultaneous detection of three groups of patients with blood lipid and blood glucose index were compared among the three groups of each index level, and using multivariate Logistic regression analysis with AS severity correlation.Results：Serum Cysc, TC, TG, FPG and 2 h PBG levels compared among the three groups, C group significantly higher than A group and B group （P〈0.05）, and B group was significantly higher than that of A group （P〈0.05）.Logistic regression analysis showed that serum Cys C, TC, TG, FPG and 2 h PBG AS were independent risk of exacerbations risk factors（OR=4.183,3.785,2.967,3.108,3.474）.Conclusion：the serum Cysc of patients with AS, there is a significant positive correlation of blood lipid and blood glucose level and the severity of the disease, the combined detection can effectively assess the patient, improve guidance for clinical diagnosis and treatment, has important value.
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