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中文摘要：
利用中国知网、万方、维普、Pub Med数据库,系统检索1949年以来关于＂十八反＂中芫花甘草反药组合同用的研究文献,检索文章的过程中剔除综述及临床研究类文章,选取实验研究方面的文章,总结归纳芫花甘草反药组合配伍使用的适宜和禁忌条件。初步认为芫花与甘草比例为1∶1为适宜条件;芫花与甘草比例小于1∶5,且总给药量较大,为禁忌条件。而给药途径、煎煮方法、炮制品种方面的研究较少,很难从少量的实验中总结归纳出宜忌条件。芫花甘草能否同用不能一概而论,而是受到不同条件的限制。在今后的科学研究中,应增加多条件交叉、多层次深入的研究,丰富和完善芫花甘草配伍的宜忌条件,进而对临床应用提供可参考的指导意见。
英文摘要：
This article summarized the suitable conditions and contraindicant conditions of antagonism compatibility genkwa flos and glycyrrhiza from the selected experimental research articles by searching “genkwa flos and glycyrrhiza compatibility of Chinese medicine Eighteen antagonism” from Wan Fang, CNKI, and VIP database since 1949. The efficacy and toxicity of the antagonism compatibility are affected by many conditions, including proportion, dose, extracting manner, prepared varieties, route of administration. We can concluded from literatures that it ’ s suitable when the ratio of genkwa flos and glycyrrhiza are 1：1; while the contraindicant conditions are when the ratios are less than 1：5 and high dose, or injecting intraperitoneally for a long time. Therefore, whether genkwa flos and glycyrrhiza can be used together or not is affected by different conditions. In the future, we can make more researches on it to enrich suitable and contraindicant conditions for genkwa flos and glycyrrhiza compatibility.
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