畜禽泻痢性疾病是畜禽常发病,严重制约着养殖业的可持续发展。本试验采用牛津杯法分别测定了复方中药制剂水提液、药典四黄止痢颗粒水提液和西药对照药物复方阿莫西林溶液对9种畜禽肠道病原菌(猪大肠杆菌K88、K99、987P,猪沙门氏菌SM2和鸡大肠杆菌O18、O37、O39,鸡沙门氏菌SM1、SM503)的抑菌试验。结果表明,所有药物对9种供试菌均有不同的抑菌效果,对9种畜禽肠道病原菌抑菌直径大小顺序分别是复方阿莫西林溶液、复方中药制剂和药典四黄止痢颗粒水提液。表明复方中药制剂对畜禽肠道致病菌有良好的抑菌作用,完全可以替代抗生素治疗该类病原菌引起的下痢性疾病。
Diarrhea is a common disease in livestock,seriously restricting the sustainable development of breeding industry.In this study,antibacterial test of Chinese herbal compound was carried out using Oxford cup method on nine kinds of poultry intestinal pathogenic bacteria,including E.coli(K88,K99 and 987P) from pigs,and E.coli(O18,O37 and O39) and Salmonella(SM1 and SM503) from chickens.Mean-while,compound amoxicillin and pharmacopoeia prescription of Sihuang Zhili Granules was set as control.The results showed the three preparations could inhibit the growth of nine kinds of bacteria in different degrees and in the order of antibacterial diameter that compound amoxicillin'sChinese medicine preparation's Sihuang Zhili particles'.Thus,it is concluded that Chinese herbal compound was capable of being a potent antibacterial agent so that it could take place of antibiotics in some degree to treat diarrhea disease caused by the nine kinds of bacteria.