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中文摘要：
目的：探讨复方术芩提取液的抗菌抗炎作用。方法：通过体外抑菌试验、小鼠耳廊二甲苯致炎试验、小鼠腹腔毛细血管通透性试验及小鼠炎症细胞渗出试验,探讨复方术芩提取液对细菌和炎症的影响。结果：复方术芩提取液在体外对大肠杆菌、金黄色葡萄球菌、猪源魏氏梭菌、沙门氏菌的MIC分别为62.50 mg/m L、31.25 mg/m L、250.00 mg/m L、125.00 mg/m L;抑菌圈直径分别为9.50 mm、16.42 mm、9.75 mm、10.75 mm;对小鼠耳廊二甲苯致炎的肿胀抑制率为82.79%,对小鼠腹腔毛细血管通透性抑制率为36.12%,对小鼠炎症细胞渗出具有抑制作用。结论：复方术芩提取液有一定的体外抑菌和抗炎效果。
英文摘要：
Objective： To study the antibacterial and antiphlogistic effects of Compound Zhuqin Extract. Methods： In vitro antibacterial experiments, auricle xylene mouse skin, capillary permeability increase and inflammatory cells seepage experiments were performed to observe the antibacterial and antiphlogistic effect of Compound Zhuqin Extract. Results： MIC of Zhuqin Extract on E.coli, Staphylococcus aureus, Clostridium perfringens and Salmonella were 62.5 mg/m L, 31.25 mg/m L, 250 mg/m L and 125 mg/m L, respectively; Bacteriostatic ring were 9.50 mm, 16.42 mm, 9.75 mm and 10.75 mm, respectively. The swelling inhibition rate of ear edema caused by xylene in mice was 82.79%, the inhibition rate of blood capillary permeability of the abdominal in mice was36.12%, also it present inhibiting effect in inflammatory cells seepage in mice. Conclusion： Compound Zhuqin Extract has certain antibacterial and anti-inflammatory effects in vitro.
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