目的:了解孕妇孕期被动吸烟和妊娠期抑郁的流行特征,并分析被动吸烟对妊娠期抑郁的影响。方法:以2013年4月-2014年3月期间分别在同济医院、硚口区妇幼保健院和东西湖人民医院产前检查(产检)和住院分娩的孕妇为研究对象,调查孕妇孕期被动吸烟暴露特征以及孕期抑郁症状的流行状况。采用Cochran-Armitage法分析被动吸烟暴露时间与抑郁症流行率的时间趋势,采用多因素Logistic回归分析被动吸烟对抑郁症的危险。结果:共调查孕妇900名,其中有效问卷791份,有效应答率为87.89%。孕期被动吸烟的暴露率为34.26%,妊娠期抑郁的流行率为17.07%,随着暴露时间增加,抑郁症的流行率呈增加趋势。孕晚期抑郁的发生率(77.04%)高于孕早中期(22.96%),差异有统计学意义(P〈0.001)。多因素Logistic回归分析显示,每日被动吸烟暴露时间超过60 min可显著增加妊娠期抑郁的发生风险(OR=4.89,95%CI:1.81-13.20)。结论:孕妇孕期被动吸烟的暴露较高,是孕妇抑郁发生的危险因素。应加强宣传教育,降低被动吸烟率,减少孕期抑郁症发生。
Objective: To understand the epidemiological characteristics of maternal passive smoking and depression during preg- nancy, analyze the effect of maternal passive smoking during pregnancy on depression. Methods: The pregnant women who gave birth to their babies in Tongji Hospital, Maternal and Child Health Care Hospital of Qiaokou District and People's Hospital of Dongxihu District from April 2013 to March 2014 were selected as study objects, the passive smoking exposure characteristics and prevalence of depression during pregnancy were surveyed. Cochran - Armitage method was used to analyze the time trend of passive smoking exposure and prevalence rate of depression ; multivariate Logistic regression analysis was used to analyze the risk of passive smoking for depression. Results: A total of 900 pregnant women were surveyed, 791 available questionnaires were obtained, the effective rate was 87.89%. The prevalence rate of passive smoking during pregnancy was 34. 26%, the prevalence rate of maternal depression was 17.07%. The prevalence rate of maternal depression showed an increasing trend with the exposure time extension. The incidence rate of depression during the third trimester of pregnancy (77. 04% ) was statistically significantly higher than those during the first and the second trimesters of pregnancy (P 〈 0. 001 ) . Multivari- ate Logistic regression analysis showed that daily passive smoking time longer than 60 minutes significantly increased the risk of maternal depression ( OR = 4. 89, 95% CI: 1.81 - 13.20) . Conclusion: Passive smoking exposure during pregnancy is high, which is a risk factor of maternal depression. Publicity and education should be strengthened and the rate of passive smoking should be reduced to decrease maternal depression.