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中文摘要：
目的探讨超声造影引导减针穿刺在降低前列腺癌穿刺活检并发症中的应用价值。方法分析我院900例可疑前列腺癌患者，其中548例行传统10点穿刺法（普通组），352例通过超声造影定位靶向病灶区，采用靶向穿刺替代部分传统穿刺点（造影组），观察对比两组前列腺癌的检出率及并发症情况。结果900例患者中共诊断前列腺癌362例（40．2％），普通组检出率38．0％（208／548），造影组检出率43．8％（154／352），两组差异无统计学意义（x2=2．99，P=0．08）。普通组穿刺次数多于造影组，差异有统计学意义（P〈0．001）。普通组发生感染等并发症134例（24．5％），造影组有56例（15．9％），普通组并发症发生率高于造影组（x2=9．39，P：0．002）。结论超声造影引导减针穿刺可减少穿刺针数，降低并发症发生率。
英文摘要：
Objective To evaluate the practical value of the method of contrast-enhanced ultrasoundguided reduced-fine needle aspiration （CEUS-FNA） in decreasing the complications of prostate nodule puncture. Methods Nine hundred patients with suspected prostate cancer（PCa） who underwent traditional 10-point blind transperineal prostate nodule puncture（ n = 548） or CEUS-FNA（ n = 352） were collected retrospectively and classfied into normal group or CEUS group, respectively. The ratio of prostate cancer diagnosis, number of punctur and compliations were observed in both groups. Results Altogether 362 PCa were diagnosed from 900 patients. Among these cases the diagnosis ratio of normal group was 38.0% （208/ 548） and that of CEUS group was 43.8% （154/352）. There was no significant difference in diagnosis ratio between two groups （X2 = 2. 992, P = 0. 084）. The puncture number of normal group were more than that of CEUS group（ P d0.01）. There were 134 cases occurred infection and other complications in tradition group and 56 cases in CEUS group. The complication rate in normal group was higher than that in CEUS group （24.5% vs 15.9%）, with significant differences between the two groups（X2 = 9.393, P = 0.002）. Conclusions CEUS-FNA could reduce puncture number, but not decrease the PCa diagnsis rate. And also that could reduce the complication rate of prostate puncture.
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