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中文摘要：
低聚糖在许多生物学事件中发挥着重要的作用。了解各种低聚糖的生物学功能，需要大量的已知结构的低聚糖，但传统的分离纯化方法限制了这种可行性。因此，采用化学和酶法合成低聚糖越来越成为当今糖生物学和糖生物技术的主流。由于低聚糖通常是以糖复合物的形式与蛋白质或脂类相连接的，为了解低聚糖分子的生物学功能，有必要研究合成新糖蛋白、新糖脂等新糖复合物的方法。作者综述了最新的酶法合成低聚糖和新糖复合物的研究进展。
英文摘要：
Oligosaccharides play important roles in many biological events. Large amount of oligosaccharides with defined structure were required for illustrating the biological functions of these oligosaccharides. These oligosaccharides are of limited availability by traditional purification methods. Chemical and enzymatic syntheses of oligosaccharides are becoming increasingly important in glycobiology and glycotechnology. Moreover, oligosaccharides often exist as glycoconjugates attached to proteins or lipids. The development of simple and effective methods for neoglycoconjugates synthesis, such as neoglycoprotein is neoglycolipids are necessary for understanding of biological functions of these molecules. The most recent developments in the enzymatic synthesis of oligosaccharides and neoglycoconjugates were summarized in this paper.
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