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中文摘要：
复方口服避孕药（COC）为最常用的避孕制剂,其含有2种性激素：孕激素和雌激素。COC可致心血管疾病。流行病调查显示COC引起的心血管疾病与血脂异常有关。其机制尚不完全清楚;三酰甘油水平的升高可能与肝脏分解脂肪和清除三酰甘油能力降低及血液中胰岛素水平增高有关。育龄期妇女长期使用时应尽可能交替使用不同种类的COC,用药期间进行血脂监测。
英文摘要：
Combined oral contraceptives are the most widely used contraceptives preparations,they contain two sex hormone： progestogen and estrogen.COC may cause cardiovascular diseases.Epidemiological evidence suggests that the dyslipidemia may be associated with these diseases.The mechanism of this phenomenon is not entirely clear;the elevation of blood triglyceride levels may be related to a decrease in lipolytic activity of liver and triglyceride removed as well as an increase in blood insulin levels.Different preparations of COC should be alternated if possible for a long-term use of the contraceptives in women of child-bearing age,and blood lipid levels should be monitored during the period of COC use.
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