目的:探讨意外抗体检测在Rh阴性患者中的分布规律及应用价值。方法:分析我院1998-2008年221 700例需要备血患者的RhD血型资料及意外抗体检测资料。结果:在221 700例患者中共检出798阴性患者(0.36%),其中出现意外抗体18例,分别为10例抗-D(1.25%)、4例抗-E(0.50%)、1例抗-S(0.125%)、1例抗-C(0.125%)、1例抗-M(0.125%),1例抗-Fyb(0.125%)。结论:对Rh阴性患者进行意外抗体检测,可以有效既可以有效保障临床安全输血的顺利实施,同时也能避免出现冰冻血液报废等输血问题。
Objective:To explore the frequency and application of unexpected antibody detection in Rh negative patients.Method:Rh blood typing and unexpected antibody detection data of 221700 cases in our in-hospital patients from 1998 to 2008 were analyzed.Result:Among 221700 patients,798 cases of Rh negative patients were detected and 18 cases of positive unexpected antibodies were found,including 10 cases of anti-D(1.25%),4 cases of anti-E,1 case of anti-S,1 case of anti-C,1 case of anti-M and 1 case of anti-Fyb,respectively.Conclusion:Detection of unexpected antibody in Rh negative patient could effectively assure the successful implementation of clinical safe transfusion and avoid some transfusion problems such as scrapped dissolved frozen blood.