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Astragalus Membranaceus Injection Combined with Conventional Treatment for Viral Myocarditis:A Systematic Review of Randomized Controlled Trials
  • ISSN号:1009-2501
  • 期刊名称:《中国临床药理学与治疗学》
  • 时间:0
  • 分类:TQ461[化学工程—制药化工] TQ925.9[轻工技术与工程—发酵工程]
  • 作者机构:[1]Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing (100730), China
  • 相关基金:Supported by the Health Industry Scientific Research Special Funding Subproject(No.200902008-04)
中文摘要:

为了估计距骨 membranaceus 的功效和安全,注射在病毒的心肌炎的处理与常规治疗结合了。

英文摘要:

Objective:To assess the efficacy and safety of Astragalus membranaceus Injection combined with conventional therapy in the treatment of viral myocarditis.Methods:Randomized controlled trials(RCTs) of A.membranaceus Injection combined with conventional treatment compared with conventional treatment alone were included.Study population characteristics and outcome results were extracted independently by two assessors.Meta-analysis was performed for data available.Results:Six RCTs,involving 639 participants,were included in this study.The methodological quality of the included trials was generally low,and there was high risk of publication bias in the included trials.The total effective rate of A.membranaceus Injection combined with conventional treatment was significantly higher than that of conventional treatment alone.Compared with conventional treatment,the cointervention treatment group showed significant recovery in myocardium enzyme levels and electrocardiography.Two RCTs reported there were no adverse effects from A.membranaceus Injection combined with conventional treatment.Conclusion:A.membranaceus Injection combined with conventional treatment appeared to be more efficacious compared with conventional treatment alone for treating viral myocarditis.However,this conclusion should be cautiously interpreted due to low methodological quality,small sample size,limited number of trials,and high risk of publication bias and other unidentified risks of bias.The safety of A.membranaceus Injection combined with conventional treatment remains uncertain.

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期刊信息
  • 《中国临床药理学与治疗学》
  • 主管单位:中国科学技术协会
  • 主办单位:中国药理学会
  • 主编:孙瑞元
  • 地址:安徽芜湖市皖南医学院弋矶山医院
  • 邮编:241001
  • 邮箱:cjcpt96@163.com
  • 电话:0553-5738350 5739333
  • 国际标准刊号:ISSN:1009-2501
  • 国内统一刊号:ISSN:34-1206/R
  • 邮发代号:26-165
  • 获奖情况:
  • 国内外数据库收录:
  • 美国化学文摘(网络版),波兰哥白尼索引
  • 被引量:17630