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中文摘要：
目的：探讨中成药与西药联用的合理性，为临床正确用药提供理论依据。方法：收集治疗心脑血管疾病常用中成药与西药合用处方92603张，进行统计分析；并结合药理学，探讨联合用药对治疗心脑血管疾病的促进作用和可能出现的不良反应。结果：在中成药与西药合用处方患者中，63％为65岁以上患者，30％为45-64岁患者，7％为45岁以下患者。不合理联合使用以及存在潜在相互作用的处方占3．49％。结论：用于治疗心脑血管疾病的中成药与西药合用处方符合率〉95％。不足5％的中成药与西药合用处方是否会导致不良反应，有待深入研究。建议进行大样本分析并结合临床观察及随访的系统研究，从而规范治疗心脑血管疾病中成药与西药的联合应用。
英文摘要：
OBJECTIVE： To investigate the rationality of Chinese patent medicine combined with western medicine, and to provide reference for rational use of drugs. METHODS： 92 603 prescriptions of Chinese patent medicine combined with western medicine in the treatment of cardiovascular and cerebrovascular disease were collected from our hospital and analyzed statistically. Based on pharmacology theory, the promotion effect of combination therapy in the treatment of cardiovascular and cerebrovascular disease and possible adverse drug reaction were investigated. RESULTS： 63% patients were over 65 years old, 30% patients were from 45 to 64 years old and the remaining patients were younger than 45 years old in the combination therapy. The rate of unreasonable use and potential interaction of Chinese patent medicine combined with western medicine was 3.49 %. CONCLUSION： The prescription compliance rate was more than 95% in combination therapy of Chinese patent medicine and western medicine for cardiovascular and cerebrovascular disease. Whether or not the less than 5 % of combination therapies lead to adverse drug reaction are needed researches. The authors suggest that systematic study of large sample, clinical observation and follow-up research should be carried out, so as to develop a standard treatment of cardiovascular and cerebrovascular diseases with combination of Chinese patent medicine with western medicine.
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