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足月剖宫产儿并发新生儿急性呼吸窘迫综合征相关危险因素分析

ISSN号：1001-4411
期刊名称：《中国妇幼保健》
时间：0
分类：R722.12[医药卫生—儿科;医药卫生—临床医学]
作者机构：盐城市妇幼保健院新生儿科,江苏盐城224002
相关基金：江苏省妇幼保健科研重点资助项目（F201209）; 江苏省妇幼保健重点学科项目（FXK 201308）

关键词：足月新生儿, 剖宫产, 急性呼吸窘迫综合征, 危险因素, Full-term neonate, Cesarean section, Acute respiratory distress syndrome, Risk factor

中文摘要：

目的探讨足月剖宫产新生儿并发急性呼吸窘迫综合征的相关危险因素。方法以足月剖宫产新生儿并发急性呼吸窘迫综合征患儿40例为研究对象,同时以40例健康足月生理产新生儿为对照组,应用单因素方差分析选择性剖宫产与非选择性剖宫产发生急性呼吸窘迫综合征有无统计学意义,应用Logistic回归分析两组新生儿在出生体重、产时窒息、胎膜早破、母亲妊娠期合并糖尿病、宫内胆汁淤积症以及哮喘有无统计学意义。结果单因素方差分析提示选择性剖宫产组ARDS发生率明显高于非选择性剖宫产组,差异有统计学意义（P〈0.05）。Logistic回归分析结果提示出生体重、产时窒息、胎膜早破、母亲妊娠期合并糖尿病、宫内胆汁淤积症以及哮喘与剖宫产儿ARDS的发生密切相关。结论选择性剖宫产是导致足月剖宫产新生儿并发ARDS的重要危险因素。产时窒息、胎膜早破、母亲妊娠合并糖尿病、宫内胆汁淤积症以及哮喘是足月剖宫产新生儿发生ARDS的危险因素,而高出生体重是足月剖宫产儿发生ARDS的保护因素。

英文摘要：

Objective To explore the related risk factors of full-term cesarean section neonates with acute respiratory distress syndrome（ ARDS）. Methods Forty full-term neonates（ cesarean section） with ARDS were selected as cesarean section group,forty healthy fullterm neonates（ vaginal delivery） during the same period were selected as control group. Univariate analysis was used to analyze the statistical significance of ARDS incidence rate between cesarean section group and control group,logistic regression analysis was used to analyze the statistical significances of birth weight,intrapartum asphyxia,premature rupture of fetal membrane,gestational diabetes mellitus,intrauterine cholestasis,and asthma during pregnancy between the two groups. Results Univariate analysis indicated that the incidence rate of ARDS in cesarean section group was higher than that in control group（ P〈0. 05）. Logistic regression analysis results suggested that birth weight,intrapartum asphyxia,premature rupture of fetal membrane,gestational diabetes mellitus,intrauterine cholestasis,and asthma during pregnancy were closely related to incidence rate of ARDS among infants born after cesarean section. Conclusion Selective cesarean section is one of the important risk factors leading to ARDS among full-term neonates. Intrapartum asphyxia,premature rupture of fetal membrane,gestational diabetes mellitus,intrauterine cholestasis,and asthma during pregnancy are the risk factors of ARDS among full-term neonates. High birth weight is a protective factor of ARDS.

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