目的:观察艾灸治疗肠易激综合征(IBS)的疗效及其镇痛效应。方法:①227例D-IBS患者随机分为温和灸组与隔药灸组,分别进行温和灸与隔药灸治疗,疗程结束后进行疗效评价和随访观察。②制备IBS样慢性内脏痛大鼠模型。观察温和灸对IBS大鼠腹部撤回反射评分(AWR)的影响结果:①温和灸组总有效率88.70%,隔药灸组总有效率88.39%,两组比较无统计学差异。随访观察:温和灸组总有效率59.13%,隔药灸组总有效率60.56%,两组比较无统计学差异。实验研究显示温和灸能显著降低IBS大鼠AWR评分结论:①艾灸治疗IBS临床有效。②艾灸能提高IBS大鼠的痛阈,具有镇痛效应。
Objective:To investigate the clinical and experimental effect of moxibustion on diarrhea-dominated irritable bowel syndrome(D-IBS).Methods:①227 patients with D-IBS were randomly divided into the Suspended Moxibustion group and the Herb-partition Moxibustion group.Clinical evaluation and follow-up visit were analyzed after the whole treatment.②The rat model of IBS was established and the abdominal withdrawal reflex(AWR)was used to evaluate visceral pain.Results:There was no difference between the two groups:effective rate was 88.70%in the Suspended Moxibustion group and the other was 88.39%;Moxibustion significantly decreased AWR in this rat model.Conclusion:①Moxibustion has clinic curative effect on D-IBS.②Moxibustion can significantly enhance pain threshold of rats with IBS.