在病人上把 electroacupuncture (EA ) 和艾灸治疗的效果与腹泻占优势的急躁的肠症候群作比较的目的(把钓饵轻轻放进水里) 。60 全部的方法 A 把钓饵轻轻放进水里病人们随机被分配到 EA 组(30 个盒子) 和艾灸组(30 个盒子) 。在治疗前后,胃肠的症状和心理症状被视觉类似物规模,布里斯托尔凳子形式规模,哈密尔顿焦虑等级规模(HAMA ) ,和评估规模(HAMD ) 的哈密尔顿消沉获得;5-hydroxytryptamine (5-HT ) 的表情, 5-HT 3 受体(5-HT3R ) ,和在 S 字形的 mucosal 织物的 5-HT 4 受体(5-HT4R ) 被染色的 immunohistochemical 测量。另外,前面的 cingulate 外皮(ACC ) 的功能的大脑区域上的效果,海岛的外皮(IC ) 和前额的外皮(陆军) 被功能的磁性的回声成像观察。与以前相比结果治疗, EA 和艾灸组腹的疼痛并且在治疗以后的腹的膨胀地报导了重要改进(P < 0.01 或 P < 0.05 ) 。艾灸组比 EA 组在澄清紧急情况,澄清频率,和凳子特征报导了更大的改进(P < 0.01 ) 。HAMA 和 HAMD 分数显著地比在 EA 组在艾灸组被减少(P < 0.01 ) 。signifificantly 表明的两个组在处理以后在结肠的 mucosa 减少了 5-HT, 5-HT3R 和 5-HT4R 的表情(P < 0.01 ) ,与在艾灸组的 5-HT 的更大的减小(P < 0.05 ) 。最后,减少了激活的 voxel 价值在治疗以后与 150 mL colorectal 扩张在刺激下面在艾灸组在左 IC ,正确 IC 和病人的陆军大脑区域被观察( P < 0.05 或 P < 0.01 ),当在 EA 组仅仅陆军区域表明了减小时( P < 0.05 )。结论艾灸能 signifificantly 改进症状把钓饵轻轻放进水里,建议那艾灸可以比 EA 为是更有效的治疗把钓饵轻轻放进水里病人。
Objective: To compare the effects of electroacupuncture (EA) and moxibustion therapies on patients with diarrhea-predominant irritable bowel syndrome (D-IBS). Methods: A total of 60 D-IBS patients were randomly allocated to the EA group (30 cases) and moxibustion group (30 cases). Before and after treatment, the gastrointestinal symptoms and psychological symptoms were scored by Visual Analogue Scale, Bristol Stool Form Scale, Hamilton Anxiety Rating Scale (HAMA), and Hamilton Depression Rating Scale (HAMD); the expressions of 5-hydroxytryptamine (5-HT), 5-HT3 receptor (5-HT3R), and 5-HT4 receptor (5-HT4R) in the sigmoid mucosal tissue were measured by immunohistochemical staining. Additionally, the effects on the functional brain areas of the anterior cingulate cortex (ACC), insular cortex (IC) and prefrontal cortex (PFC) were observed by functional magnetic resonance imaging. Results: Compared with before treatment, both EA and moxibustion groups reported significant improvements in abdominal pain and abdominal bloating after treatment (P〈0.01 or P〈0.05). The moxibustion group reported greater improvements in defecation emergency, defecation frequency, and stool feature than the EA group (P〈0.01). Both HAMA and HAMD scores were significantly decreased in the moxibustion group than in the EA group (P〈0.01). Both groups demonstrated significantly reduced expressions of 5-HT, 5-HT3R and 5-HT4R in the colonic mucosa after treatment (P〈0.01), with a greater reduction of 5-HT in the moxibustion group (P〈0.05). Finally, decreased activated voxel values were observed in the left IC, right IC and PFC brain regions of patients in the moxibustion group under stimulation with 150 mL colorectal distension after treatment (P〈0.05 or P〈0.01), while in the EA group only PFC area demonstrated a reduction (P〈0.05). Conclusion: Moxibustion can significantly improve the symptoms of D-IBS, suggesting that moxibustion may be a more