中文摘要：

ObjectiveTo 调查温暖艾灸 Tianshu 的效果(圣 25，双边) 并且在有腹泻主导的急躁的肠症候群的病人的 Qihai (CV 6 )( 把钓饵轻轻放进水里) 由估计占优势的因素，并且决定最好的因素联合和他们的相互作用。识别温暖艾灸 Tianshu 的最佳的数量(圣 25，双边) 并且 Qihai (CV 6 ) 到完成最佳的 efficacy.MethodsAn L9 (3 ⁴) 直角的设计基于三个很有影响的因素和三个最经常使用的层次被用于 233 个证实的题目。九个节目被设计。题目根据年龄和性被分到四亚群；每个题目随机经历了九个节目之一。我们选择了 Tianshu (圣 25，双边) 并且 Qihai (CV 6 ) 。症状的分数和生活(IBS-QOL ) 的 IBS 质量在最后的 treatment.ResultsAfter 治疗以后被评估，所有病人的临床的症状显著地被改进(P = 0.001 ) 。生活的质量也显著地改善了(P < 0.05 ) 。为所有参加者，频率是关于症状的统治因素(P = 0.01 ) 。持续时间是为生活的质量的统治因素(P = 0.0001 ) 。为在 30-40-year-old 男性和女病人改进症状的最好的联合一天各是 10 min 的二堂功课一次，并且为男性的 41-50-year-old 和女病人，它是 10 min (男性) 或 30 min (女性) 的三堂功课两次一天。为生活的质量的最好的联合一天是 20 min 的三堂功课一次。没有相互作用在频率之间被发现并且路线，或频率和 duration.ConclusionWarming 艾灸 Tianshu (圣 25，双边) 并且 Qihai (CV 6 ) 是有希望的治疗为把钓饵轻轻放进水里。获得最佳的功效，温暖的艾灸的三个主要因素(持续时间，频率和治疗路线) 应该到达特定的数量并且适当地被联合。

英文摘要：

OBJECTIVE： To investigate the effects of warming moxibustion Tianshu（ST 25, bilateral） and Qihai（CV6） in patients with diarrhea-dominant irritable bowel syndrome（D-IBS） by assessing predominant factors, and determining the best factor combinations and their interactions. To identify the optimal quantity of warming moxibustion Tianshu（ST 25, bilateral） and Qihai（CV 6） to achieve optimal efficacy.METHODS： An L9（3~4） orthogonal design was applied to 233 confirmed subjects based on the three most influential factors and the three most frequently used levels. Nine programs were designed.Subjects were assigned to four subgroups according to age and gender; each subject underwent one of the nine programs randomly. We selected Tianshu（ST 25, bilateral） and Qihai（CV 6）. The scores of symptoms and the IBS Quality of Life（IBS-QOL） were evaluated after the final treatment.RESULTS： After treatment, clinical symptoms of all patients were significantly improved（P = 0.001）.Quality of life also improved significantly（P 〈 0.05）.For all the participants, frequency was the dominating factor regarding symptoms（P = 0.01）. Duration was the dominating factor for quality of life（P =0.0001）. The best combination for improving symptoms in 30-40-year-old male and female patients was two courses of 10 min each once a day, and for41-50-year-old male and female patients it was three courses of 10 min（males） or 30 min（females）twice a day. The best combination for quality of life was three courses of 20 min once a day. No interaction was found between frequency and course, or frequency and duration.CONCLUSION： Warming moxibustion Tianshu（ST25, bilateral） and Qihai（CV 6） is a promising therapy for D-IBS. To acquire optimal efficacy, the three main factors（duration, frequency and treatment course） of the warming moxibustion should reach a specific quantity and be combined appropriately.