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中文摘要：
机体免疫功能的异常是炎症性肠病发病的机理之一，艾灸疗法可通过调节机体免疫功能实现对炎症性肠病的防治作用。本文从肠道菌群失调在炎症性肠病发病中的作用、模式识别受体与炎症性肠病的关系、模式识别受体信号转导途径及艾灸调整机体免疫功能的优势等几方面进行论述，认为肠道菌群失调、模式识别受体及其信号转导通路对炎症性肠病的发生发展具有重要意义，采用微生物学和免疫学等现代科学技术，研究艾灸对模式识别受体及其信号转导通路的影响是深入阐释艾灸治疗炎症性肠病作用机理的重要途径。
英文摘要：
Immunologic dysfunction is one of the pathogeneses of inflammatory bowel disease. Moxibustion can produce preventive and therapeutic effects on inflammatory bowel disease by regulating body immunologic function. The article deals with the action of intestinal flora alteration in the development of inflammatory bowel disease, the relationship between pattern recognition receptors and inflammatory bowel disease, pattern recognition receptor signal transduction pathway, and the advantages of moxibustion regulation of body immunologic function. It is considered that the alteration of intestinal flora, pattern recognition receptors and signal transduction pathway have great significance for the development of inflammatory bowel disease. Using modem microbiological and immunological techniques to study the effect of moxibustion on pattern recognition receptors and their signal transduction pathway is an important way to further explain the mechanism of therapeutic action of moxibustion on inflammatory bowel disease.
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