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Influences of Motion Artifacts on Three-Dimensional Reconstruction Volume and Conformal Radiotherapy Planning

ISSN号：1004-0552
期刊名称：《中国生物医学工程学报：英文版》
时间：0
分类：R730.55[医药卫生—肿瘤;医药卫生—临床医学]
作者机构：[1]Department of Radiotherapy Center, the Affiliated Tumor Hospital of Guangzhou Medical College, Guangzhou 510095, China, [2]School of Biomedical Engineering,Southern Medical University, Guangzhou 510515, China
相关基金：Guangzhou Municipal Medicin ＆ Health Program ;Grant number ：2006-YB-177

作者： ZHANG Shu-xu[1,2], CHEN Guang-jie[2], ZHOU Ling-hong[2], YANG Ke-cheng[2], LIN Sheng-qu[2]

关键词：放射线疗法, 医学图像, 图像处理, 三维重建, motion artifact, phantom, three-dimensional conformal radiation therapy （ 3 D-CRT） , four-dimensional computed tomography （ 4 D-CT）

中文摘要：

客观：调查运动人工制品的影响在上三维(3D ) 重建体积和保角的放射疗法计划。方法：能沿着头部尾的方向模仿肺肿瘤的片断运动的一个幽灵被步进马达构造，聚乙烯和土豆的小球。十个不同扫描协议被设置，幽灵的 CT 数据被使用一台商业 GE LightSpeed16 CT 扫描仪获得。CT 数据的 3D 重建被采用 GE AdvantageSim 6.0 系统的显示卷的技术实现。在不同扫描协议的每个目标的重建的体积通过测量工具的 3D 被测量。因此，在动人的目标和静态的之间的重建体积的相对偏差是坚定的。三维的保角的放射治疗(3DCRT ) 计划和保角的地与计划系统(TPS ) 的 WiMRT 处理为一个静态 / 动人的目标被创造并且比较。结果: 为一个静态的目标，当 CT 数据与不同程度和片被获得时，在 3D 重建卷之中没有明显的差别。3D 重建体积和 3D 的外观一个动人的目标的保角的地与静态的的相当不同。最大的相对偏差为与不同扫描协议扫描的一个动人的目标是将近 90% 。相对偏差在不同目标之中是可变的，关于从-39.8%到89.5%为一个更小的目标并且从-18.4%到20.5%为更大的 one.Conclusion :运动人工制品在 3D-CRT 计划和重建体积上有大效果，它将极大地为一个动人的目标导致弄歪的保角的放射域和假 DVH 。

英文摘要：

Objective ：To investigate the influences of motion artifacts on three-dimensional （3D） reconstruction volume and conformal radiotherapy planning. Methods： A phantom which can mimic the clip motion of lung tumor along the cranial-caudal direction is constructed by step motor, small ball of polyethylene and potato. Ten different scan protocols were set and CT data of the phantom were acquired by using a commercial GE LightSpeedl6 CT scanner. The 3D reconstruction of the CT data was implemented by adopting volume-rendering technology of GE AdvantageSim 6.0 system. The reconstructed volumes of each target in different scan protocols were measured through 3D measuring tools. Thus, relative deviations of the reconstruction volumes between moving targets and static ones were determined. The three-dimensional conformal radiation therapy （3D- CRT） plans and conformal fields were created and compared for a static/moving target with the WiMRT treatment planning system （TPS）. Results：For a static target, there was no obvious difference among the 3D reconstruction volumes when the CT data were acquired with different pitches and slices. The appearance of 3D reconstruction volume and 3D conformal field of a moving target was quite different from that of static one. The maximum relative deviation is nearly 90% for a moving target scanned with different scan protocols. The relative deviations are variable among the different targets, about from -39.8% to 89.5% for a smaller target and from - 18.4% to 20.5% for a larger one. Conclusion ：The motion artifacts have great effects on 3 D-CRT planning and reconstruction volume, which will greatly induce distorted conformal radiation fields and false DVHs for a moving target.