目的探讨生活方式干预对糖耐量减退(IGT)高危人群糖耐量的影响,为预防糖尿病提供依据。方法选取葡萄糖耐量减退患者40例,随机分为生活方式干预组和对照组各20例。生活方式干预组患者接受个体化的饮食和体力活动指导,干预患者的生活方式;对照组接受常规的健康教育。随访1年,比较干预前后2组糖代谢变化情况。结果随访1年后,干预组的空腹血糖显著改善,与干预前比较,差异有统计学意义(P〈0.05)。干预组口服葡萄糖耐量试验(OGTT)2h血糖指标亦较干预前显著改善由(9.9±1.5)mmol/L下降至(9.1±1.6)mmol/L。对照组上述指标改善程度不显著。结论生活方式干预能降低空腹血糖和餐后血糖,延缓和减少2型糖尿病的发生。
Objective In order to investigate the impact of life style interventions on glucose tolerance in relatively high-risk population of IGT,and provide evidence for prevention of IGT. Methods Divided 40 individuals of IGT into control group (20 cases) and life style intervention group (20 cases). The cases in the lifestyle group had accepted the individual training and diet education, while the traditional health education was used in control group. Oneyear follow-up was carried out to know the changes of blood glucose concentration between the two groups. Results Fast blood glucose and the OGTT were improved significantly in life style intervention group,P〈0.05, while these indexes in the control group were not changed significantly. Conclusion Life style intervention could decrease the levels of fast blood gluse, and then retard and decrease the incidence rate of type 2 diabetes .