目的:探讨新生儿窒息的原因以及窒息后并发多脏器损害的发生率及临床相关危险因素。方法:选取南方医科大学附属潮州市中心医院2011年10月-2013年10月收治的136例新生儿窒息的临床资料进行分析,查找引起新生儿窒息的主要原因,并将新生儿窒息分为轻度窒息组(98例)和重度窒息组(38例),对其多脏器损害发生率及危险因素进行分析,应用χ2检验和回归分析找出新生儿窒息程度与多脏器损害的相关性。结果:羊水混浊为新生儿窒息的首要原因,其次为脐带绕颈。重度窒息组中多脏器损害的发生率为明显高于轻度窒息组(P〈0.05),且窒息后多脏器损害的发生与窒息程度、合理复苏、羊水混浊、脐带绕颈明显相关。结论:找到适于减少新生儿窒息的措施,加强对新生儿窒息病因及相关治疗的研究,进一步加强监护及产、儿科的合作,对进一步降低新生儿窒息的发生率、病死率及致残率,防止多脏器损害的发生,提高对新生儿窒息的复苏抢救和治疗成功率具有十分重要的临床价值。
Objective To explore the causes of asphyxia of newborn, the incidence rate and correlated risk factors for anoxianewborn complicated with multi-organ damage Methods Analyze the clinc data of 136 anoxia newborn which were from October2011 to October 2013 in Affiliated Chaozhou Central Hospital of Southern Medical University and find the major cause of asphyxiaof newborn.The anoxia newborn were chosen for case group,which were divided into mild asphyxia group and severe asphyxiagroup,incidence rate and correlated risk factors were analyzed for anoxia newborn complicated with multiorgan damage, use_2test and regresson analysis to find out the correlation between the apnoea degree and multi-organ damage. Results The amnioticfluid turbidity was the leading cause of neonatal asphyxia, followed by umbilical cord around the neck..The incidence of multi-organdamage in severe asphyxia group was obviously higher than that of mild asphyxia group(P〈0.05), multiorgan damage was correlatedto apnoea degree,reasonable anabiosis,amniotic fluid turbidity, umbilical cord around the neck after asphyxia. Conclusion Findthe suitable measures to reduce the neonatal asphyxia,strengthen the research of neonatal asphyxia etiology and treatment,furtherstrengthen guardianship and cooperation of obstetrics-pediatrics,which have important clinical value for further reducing incidencerate,mortality and disability rate of neonatal asphyxia and preventing the occurrence of multi-organ damage,improving the successrate of anabiosis and treatment of neonatal asphyxia.